Self-Regulation and Toxic Stress: A Comprehensive Review

By Aleta L. Meyer, PhD

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Aleta L. Meyer is Senior Social Science Research Analyst, Office of Planning, Research and Evaluation Administration for Children and Families, U.S. Department of Health and Human Services. Meyer’s work focuses on the translation of theory and empirical research across multiple health outcomes into effective and feasible prevention programs for communities. At Administration for Children and Families (ACF) this includes the translation of research on early adversity to ACF programs, community-based-participatory-research to evaluate early childhood programs within American Indian/Alaska Native communities, and positive youth development.

In March 2015 we featured the first of 4 inter-related reports on self-regulation and toxic stress published by the Duke Center for Child and Family Policy, titled Seven Key Principles Identified in New Report on Self-Regulation Development, by Meyer who conceived the project, led the effort, and is the project’s program officer.

Since that time, the project published a second report, A Review of Ecological, Biological, and Developmental Studies of Self-Regulation and Stressa literature review on the impact of early adversity and chronic stress on self-regulation development from birth to young adulthood.

This post by Meyer, highlights the recently released 3rd report, Self-Regulation and Toxic Stress Report 3: A Comprehensive Review of Self-Regulation Interventions from Birth Through Young Adulthood. Key authors: Desiree W. Murray, Katie self-reg-coverRosanbalm, Christina Christopoulos, Center for Child and Family Policy, Duke University.
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Restorative Practices and The 3 R’s – Restore, Rebuild, Reconnect

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This month’s blog is by Mark Marini, known to most as “Muggsie,” an Intervention Specialist at Albemarle High School. For the past 19 years, he has worked diligently in education to support struggling learners, both with behaviors and academics, by working both with students and teachers. He fills many roles at Albemarle High including: Intervention Specialist, English teacher, Special Education teacher, Mediator, School Based Intervention Co-Chair, Response To Intervention Specialist, AVID English teacher, and lifelong learner. Check out his blog, On Education.

Youth-Nex had the pleasure of meeting Muggsie at this year’s conference, “Youth of Color Matter: Reducing Inequalities Through Positive Youth Development.” We are grateful for his and fellow educators’ participation at the event.

There are some children in the world who were just born to be good. My daughter, who is now nine, seems to be one of those children. When she was small, still crawling around, my wife and I remember her going past an electrical outlet in our house. She started to reach towards it, and my wife gently said, “No; don’t touch.” She looked at my wife, looked at the outlet, and kept crawling. Several days later, she was crawling past the same outlet, and she stopped. Pointed at it and said, “No.” Then she continued crawling. For the most part, my wife and I did not have to teach her good behavior. It is as if she was born with a gene that helps her to do the right thing. But that does not mean she always does.


“My experience is that Restorative Practices, if implemented with the required support and training, can have a great impact on a community. This could be a school, a neighborhood, or even a family. With time and dedication, the gains for our next generation are great. For, while resolving conflicts with Restorative Practices, we teach children how to resolve future conflicts on their own.”


SomeWalkingAwaytimes, she needs additional support. She has a younger brother who tests her and her ability to make the right choices. In those moments when she is tested, she needs support to know how to act, and how, if she has caused harm, to fix it.

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Seven Key Principles Identified in New Report on Self-Regulation Development

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“Kids at Kubota Garden 2003” by Seattle Municipal Archives from Seattle, WA. Licensed under CC BY 2.0 via Wikimedia Commons

We are pleased to share the first in a series of four inter-related reports on Self-Regulation and Toxic Stress from the Duke Center for Child and Family Policy. In the current report, the authors introduce and describe a set of seven key principles that summarize their understanding of self-regulation development in context.

Aleta L. Meyer, Ph.D., of the Office of Planning, Research and Evaluation Administration for Children and Families at the U.S. Department of Health and Human Services, conceived the project, led the effort, and is the project’s program officer.

Key Authors:
Desiree W. Murray, Ph.D., Research Scientist, Center for Child and Family Policy, Duke University, Scientist and Associate Director of Research, Frank Porter Graham Child Development Institute, University of North Carolina at Chapel Hill. Desiree.murray@unc.edu
Katie Rosanbalm, Ph.D., Research Scholar, Center for Child and Family Policy, Duke University. Katie.rosanbalm@duke.edu

Self-regulation has become increasingly recognized for its foundational role in promoting wellbeing across the lifespan, including physical, emotional, social and economic health and educational achievement.  Given this growing knowledge base and a desire to inform on-going services for children and youth from birth to young adulthood, the Office of Planning, Research, and Evaluation at the Administration for Children and Families commissioned a series of four inter-related reports from a team at the Center for Child and Family Policy at Duke University; the series is titled Self-Regulation and Toxic Stress.

The first report from that series, Foundations for Understanding Self-Regulation from an Applied Developmental Perspective, is now available and provides a comprehensive framework for understanding self-regulation in context, using a theoretical model that reflects the influence of biology, caregiving, and the environment on the development of self-regulation from birth to young adulthood. In that report, the authors introduce and describe a set of seven key principles that summarize our understanding of self-regulation development in context:

  1. Self-regulation serves as the foundation for lifelong functioning across a wide range of domains, from mental health and emotional wellbeing to academic achievement, physical health, and socioeconomic success. It has also proven responsive to intervention, making it a powerful target for change.
  2. Self-regulation is defined from an applied perspective as the act of managing cognition and emotion to enable goal-directed actions such as organizing behavior, controlling impulses, and solving problems constructively.
  3. Self-regulation enactment is influenced by a combination of individual and external factors including biology, skills, motivation, caregiver support, and environmental context. These factors interact with one another to support self-regulation and create opportunity for intervention.
  4. Self-regulation can be strengthened and taught like literacy, with focused attention, support, and practice opportunities provided across contexts. Skills that are not developed early on can be acquired later, with multiple opportunities for intervention.
  5. Development of self-regulation is dependent on “co-regulation” provided by parents or other caregiving adults through warm and responsive interactions in which support, coaching, and modeling are provided to facilitate a child’s ability to understand, express, and modulate their thoughts, feelings, and behavior.
  6. Self-regulation can be disrupted by prolonged or pronounced stress and adversity including poverty and trauma experiences. Although manageable stress may build coping skills, stress that overwhelms children’s skills or support can create toxic effects that negatively impact development and produce long-term changes in neurobiology.
  7. Self-regulation develops over an extended period from birth through young adulthood (and beyond). There are two clear developmental periods where self-regulation skills increase dramatically due to underlying neurobiological changes– early childhood and adolescence – suggesting particular opportunities for intervention.

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